B-Cor 10 tabl. #30

What is the active ingredient in B-Cor 10 tablets?

Bisoprolol fumarate

How many mg of Bisoprolol fumarate are in one tablet of B-Cor 10?

10 mg

How often should B-Cor 10 tablets be taken?

Once daily

What is the maximum daily dosage of B-Cor 10 tablets?

2 tablets (20 mg)

How should B-Cor 10 tablets be taken?

Swallow whole with some liquid, preferably in the morning on an empty stomach or with breakfast.

For what conditions is B-Cor 10 prescribed?

High blood pressure (hypertension) and Coronary heart disease (angina pectoris)

In what cases should B-Cor 10 not be used?

Untreated myocardial insufficiency (decompensated heart failure), recent myocardial infarction, shock, disturbances of atrioventricular conduction (AV block grades II and III), sick sinus syndrome, disturbed stimulus conduction between the sinoatrial node and atrium (sinoatrial block), extremely slow pulse (bradycardia with less than 50 beats/min) prior to the start of treatment, extremely low blood pressure (hypotension), bronchial asthma and advanced stages of peripheral circulatory disturbances, untreated phaeochromocytoma, pregnancy or lactation, and children.

What drugs can interact with B-Cor 10?

Other antihypertensive drugs, reserpine, methyldopa, clonidine, guanfacine, nifedipine, calcium antagonists of the verapamil or diltiazem type, other antiarrhythmic agents, rifampicin, insulin, oral antihyperglycaemic agents.

What are the potential consequences of using B-Cor 10 with other antihypertensive drugs?

Potentiation of the antihypertensive effect, leading to excessive blood pressure lowering.

What precautions should be taken when using B-Cor 10 with nifedipine?

Careful monitoring is required as the combination can potentiate the antihypertensive effect.

What should be avoided when using B-Cor 10 with calcium antagonists and antiarrhythmic agents?

Intravenous administration of these agents is not recommended due to the risk of hypotension, bradycardia, and other arrhythmias.

What is the effect of rifampicin on B-Cor 10?

It can slightly reduce the half-life of Bisoprolol, but an increase in dosage is generally not necessary.

What should be considered when using B-Cor 10 with insulin or oral antihyperglycaemic agents?

The effect of these agents may be potentiated, and blood-glucose levels should be monitored regularly.

What are the most common side effects of B-Cor 10?

Tiredness, dizziness, mild headaches, perspiration, sleep disturbances, vivid dreams, depressive moods. These usually subside within 1-2 weeks.

What are some less common side effects of B-Cor 10?

Gastrointestinal disturbances (diarrhea, constipation, nausea, abdominal pain), skin reactions (erythema, pruritus), marked decrease in blood pressure, slow pulse rate, disturbance of AV conduction, tingling and a sensation of coldness in the limbs, muscle weakness, muscle cramp, reduced lacrimation, aggravation of intermittent claudication and Raynaud's phenomenon, intensification of myocardial insufficiency, difficulties in breathing in patients prone to bronchospastic reactions, impairment of glucose tolerance in elderly diabetic patients.

What precautions should be taken with B-Cor 10?

Careful monitoring of blood pressure and pulse rate, particularly at the start of treatment and with dosage changes. Inform the anaesthetist if the patient is taking B-Cor 10 before surgery or anesthesia. Exercise caution in diabetic patients, as B-Cor 10 can mask the symptoms of hypoglycaemia.

What measures should be taken in case of overdosage?

Discontinue B-Cor 10 and administer appropriate antidotes if necessary: atropine intravenously, orciprenaline slowly intravenously, and glucagon.

How long is treatment with B-Cor 10 typically required?

Long-term therapy

How should B-Cor 10 treatment be discontinued?

Gradually, under the supervision of a doctor, especially in patients with coronary artery disease. Abrupt discontinuation can be dangerous.

What are the storage conditions for B-Cor 10?

Store below 30°C.

How is B-Cor 10 presented?

3 x 10 film-coated tablets.

What is the manufacturer of B-Cor 10?

Afrab-Chem Ltd., Nigeria.