Amlodipine Besylate USP, equivalent to 5mg of Amlodipine.
Inhibits calcium influx into cardiac and vascular smooth muscle, relaxing vascular smooth muscle, reducing peripheral resistance and lowering blood pressure.
Peripheral edema, palpitations, dizziness, headache, somnolence, nausea, abdominal pain, fatigue, flushing.
Hypersensitivity to Amlodipine or dihydropyridines.
Start with a lower dose and monitor closely due to decreased clearance of Amlodipine.
Mild renal impairment does not significantly affect Amlodipine concentrations. Severe impairment may require dosage reduction.
Patients with hepatic impairment have prolonged Amlodipine half-life, requiring lower doses.
5mg once daily, increasing to 10mg after 10-14 days if needed.
Store at a temperature not exceeding 30°C in a dry place, protected from light.
Manufactured by Baroque Pharmaceuticals Pvt. Ltd. in India, marketed by Pharma Nigeria Max Limited.