Amoxil 250 mg capsules #100

1. What is the strength and packaging size of Amoxil capsules being described?

250 mg and 500 mg strengths; 100 capsules per package.

2. What is the active ingredient in Amoxil and its chemical form?

Amoxicillin trihydrate.

3. What are the common gastrointestinal side effects of Amoxil?

Diarrhea and nausea.

4. What are some rare but serious side effects of Amoxil?

Severe allergic reactions (angioneurotic edema, anaphylaxis, serum sickness, hypersensitivity vasculitis), Stevens-Johnson Syndrome, toxic epidermal necrolysis, antibiotic-associated colitis, blood disorders (reversible leucopenia, thrombocytopenia, haemolytic anaemia), hepatitis, and cholestatic jaundice.

5. What precautions should be taken before starting Amoxil treatment?

Enquire about hypersensitivity to penicillins or cephalosporins; avoid if infectious mononucleosis is suspected; caution with phenylketonuria and sugar intolerance.

6. How should Amoxil dosage be adjusted for patients with renal impairment?

Dosage adjustments are necessary based on creatinine clearance levels.

7. What are the standard dosages for adults and children?

Adults/children >40kg: 250mg TID, increasing to 500mg TID. Children <40kg: 125mg TID, increasing to 250mg TID.

8. What is the recommended dosage of Amoxil for the prophylaxis of endocarditis?

Adults/children >40kg: 2g single oral dose 30-60 minutes before procedure. Children <40kg: 50mg/kg single oral dose 30-60 minutes before procedure.

9. What are some examples of infections Amoxil is commonly used to treat?

Respiratory tract infections, gastrointestinal infections, genitourinary infections, skin and soft tissue infections, Lyme disease, gonorrhea, and septicemia.

10. Can Amoxil be used during pregnancy and lactation?

Yes, with caution. Benefits must outweigh risks.

11. How is Amoxil eliminated from the body?

Primarily through the kidneys (60-70% in urine), also in feces and bile.

12. How should the oral suspension be prepared?

Invert and shake bottle, add water below the mark, shake, top up to mark, shake again. Shake before each dose. Use within 7 days and store refrigerated.

13. What are the symptoms of an Amoxil overdose, and how is it treated?

Gastrointestinal symptoms (nausea, vomiting, diarrhea), water/electrolyte imbalances. Treat symptomatically. Hemodialysis can remove Amoxil.

14. Are there any potential drug interactions with Amoxil?

Yes, with probenecid, oral contraceptives, allopurinol, and anticoagulants. May cause false positive urine glucose tests.

15. What is the mechanism of action of Amoxil?

Inhibits bacterial cell wall mucopeptide biosynthesis. Ineffective against beta-lactamase-producing organisms.