Miconazole Nitrate B.P. 2% w/w
A synthetic antifungal agent.
It interferes with the fungal cell membrane by inhibiting ergosterol synthesis and altering lipid composition, leading to fungal cell death.
Common dermatophytes (Trichophyton rubrum, Trichophyton mentagrophytes, Epidermophyton floccosum), yeasts (Candida albicans), Malassezia furfur, and various other fungi.
Yes, it has activity against certain gram-positive bacteria like staphylococci and streptococci.
Yes, it has proven efficacy in treating secondary infected mycoses.
It's indicated for fungal infections of the skin and nails, including: Tinea pedis (athlete's foot), Tinea corporis, Cutaneous candidiasis (monilliasis), Tinea versicolor, Ringworm, Onychomycosis , Vaginal candidiasis
Twice daily (morning and evening) for most conditions, except for Tinea versicolor, which requires once-daily application.
Treatment duration varies depending on the condition: Tinea pedis: 1 month, Tinea cruris, tinea corporis, cutaneous candidiasis: 2 weeks after symptom relief.
Isolated reports of local irritation and allergic contact dermatitis.
Discontinue use of the medication.
It comes in a 50 ml tamper-evident HDPE container.
Store below 30°C and away from children.
Yes, it is for external use only.
Afrab-Chem Ltd., Nigeria.