Dissolve one sachet of Artesunate 25mg (white) and one sachet of Amodiaquine 75mg (orange) in 10ml of clean water. This mixture should be given once daily for three days.
Camosunate is a combination of Artesunate and Amodiaquine.
Dissolve one sachet of Artesunate 50mg (white) and one sachet of Amodiaquine 150mg (pink) in 10ml of clean water. This mixture should be given once daily for three days.
Known hypersensitivity to Artesunate or Amodiaquine, history of fever disease or blood impairment during previous amodiaquine treatment, retinopathy (with frequent amodiaquine treatment), and pregnancy (especially the first trimester). Use during breastfeeding is not recommended.
Artesunate side effects are generally rare and may include slight changes in hematology values, a mild and transient reduction in sinus heart rate, and abdominal cramps and mild diarrhea at high doses. Amodiaquine side effects may include neurological effects (lethargy, drowsiness, involuntary movements), hepatitis in hypersensitive individuals, nausea, vomiting, diarrhea, agranulocytosis, and other blood dyscrasias. Amodiaquine should be used with caution in patients with liver disease or alcoholism, or those taking hepatotoxic drugs.
Stop treatment immediately and consult a doctor or pharmacist. Symptoms of overdose may include headache, dizziness, visual disturbances, and convulsions.
Store in the original packaging below 30°C and protect from moisture. Do not use after the expiration date printed on the package.
Camosunate works through the synergistic action of artesunate and amodiaquine. It is highly effective against the asexual forms of the malaria parasite (Plasmodium), including schizonts and gametocytes. This action rapidly clears parasitemia, leading to quick clinical recovery and preventing further infestation.
Camosunate is indicated for the treatment of acute uncomplicated malaria, including multi-drug resistant strains of P. falciparum.
It is manufactured by FRONT PHARMACEUTICAL PLC. in Xuancheng Economic and Technical Development Zone, Anhui, China. It is marketed by Geneith Pharm. Limited in Lagos, Nigeria.
No negative drug interactions have been reported. Studies have shown that the combination of artesunate and amodiaquine significantly improves cure rates.
Use during pregnancy is not recommended, particularly during the first trimester, unless the benefits outweigh the risks as determined by a doctor (e.g., in cases of cerebral malaria). Artesunate is not known to cross into breast milk, but use during breastfeeding is not recommended.