E Mal-75 sol. for inj. 1.0 ml #3

What is E MAL-75 (a-ß Arteether) and what is it used for?

E MAL-75 (a-ß Arteether) is a synthetic derivative of artemisinin, used for treating chloroquine-resistant *Plasmodium falciparum* malaria.

What is the recommended dosage of E MAL-75 (a-ß Arteether) for adults and children?

Adults: 150 mg (2 ampoules) once daily for 3 days. Children: 3 mg/kg per day intramuscularly for 3 days.

How is E MAL-75 (a-ß Arteether) administered?

Deep intramuscular injection in the upper-external buttock quadrant.

How does E MAL-75 (a-ß Arteether) work to treat malaria?

It targets the *Plasmodium falciparum* parasite, disrupting its ability to survive and multiply.

Are there any precautions for using E MAL-75 (a-ß Arteether)?

Caution is advised during pregnancy and breastfeeding. It doesn't interfere with most antimalarials but should not be combined with other artemisinin derivatives.

What are the common side effects of E MAL-75 (a-ß Arteether)?

Neurotoxicity, nausea, dizziness, depressed gastrointestinal activity.

What is the storage requirement for E MAL-75 (a-ß Arteether)?

Store below 30°C and protected from light.

What is the presentation of E MAL-75 (a-ß Arteether)?

3x1 ml ampoules.

What are the contraindications for E MAL-75 (a-ß Arteether)?

Hypersensitivity to artemisinin derivatives.

What is the clinical data supporting the use of E MAL-75 (a-ß Arteether)?

Clinical trials have shown effectiveness in treating both uncomplicated and complicated malaria, with high cure rates and rapid symptom resolution.