Havax 24 tabl. #24

What is Havax and what is it used for?

Havax is a combination medication containing Artemether and Lumefantrine used to treat acute uncomplicated malaria.

How does Havax work against malaria?

Artemether and Lumefantrine interfere with the malaria parasite's heme conversion process and inhibit nucleic acid and protein synthesis.

How should Havax be taken?

Orally with fatty food or drinks twice daily for three days. Dosage is based on body weight.

What are the contraindications for using Havax?

Hypersensitivity to ingredients, severe malaria, certain drug interactions (CYP2D6 substrates, QTc prolonging drugs, strong CYP3A4 inducers).

What are the potential drug interactions with Havax?

QTc prolonging drugs, CYP2D6 substrates, strong CYP3A4 inducers, hormonal contraceptives, quinine, mefloquine.

What are the potential side effects of Havax?

Headache, dizziness, decreased appetite, palpitations, vomiting, abdominal pain, nausea, joint pain, and fatigue.

What should be done in case of an overdose?

Symptomatic and supportive therapy, including ECG and blood potassium monitoring.

What are the pharmacokinetic properties of Havax?

Artemether is rapidly absorbed and metabolized. Lumefantrine's absorption is slower and has a longer half-life. Food enhances absorption of both.

Can Havax be used during pregnancy or lactation?

Not recommended, especially during the first trimester of pregnancy or while breastfeeding.

How should Havax be stored?

Below 30°C, protected from light and moisture, and out of reach of children.