Chloroquine Phosphate BP, equivalent to 40mg of Chloroquine Base per ml.
Aminoquinoline antimalarials.
It primarily targets the erythrocytic forms of malaria parasites, killing them at all stages of development. The exact mechanism is unclear, but it likely involves interaction with DNA and inhibition of certain enzymes.
It is effective against susceptible strains of Plasmodium vivax, P. malariae, P. ovale, and susceptible strains of P. falciparum. It is used for both prophylaxis (prevention) and treatment of malaria.
Treatment of extraintestinal amebiasis, management of inflammatory disorders.
Known hypersensitivity to chloroquine or any other ingredients of the formulation, concomitant use with amiodarone.
Amiodarone, antacids and adsorbents, ciclosporin.
Intramuscular (IM) or slow intravenous (LV).
Ocular, Neuromuscular, Auditory, Gastrointestinal, Dermatologic, CNS, Cardiovascular.
Treatment is symptomatic and supportive.
Store in a cool place at a temperature not exceeding 25°C. Protect from light.
There is evidence that high doses of Chloroquine during pregnancy may cause fetal abnormalities. Chloroquine is excreted in breast milk, but the amount is considered too small to be harmful for prophylaxis.
Consider official guidelines and local information on antimalarial drug resistance, use with caution in patients with hepatic disease, monitor complete blood cell counts during prolonged therapy.
10 x 30 ml vials packed in a carton along with a patient information leaflet.