Answer: Chloroquine Phosphate B.P. 80mg, a 4-aminoquinoline anti-immune agent.
Answer: Immune System Diseases like Lupus Erythematosus, liver amoebiasis, and Photosensitivity.
Answer: Patients with previous intolerance to the drug, impaired liver or renal function, porphyria, or psoriasis.
Answer: It inhibits the release or activity of cytokines involved in the inflammatory process, acting as an anti-immune agent.
Answer: Adults: 600mg of Chloroquine base daily for 2 days, then 300mg daily for 2 weeks. Children: 6mg/kg daily, up to a maximum of 300mg daily.
Answer: Maxiquine Syrup should be taken with food as it improves absorption.
Answer: Adults: 150mg (maximum 2.5mg/kg) of base daily. Children: Up to 3mg/kg daily.
Answer: Increased risk of ventricular arrhythmias when used with halofantrine, amiodarone, or moxifloxacin. Increased risk of convulsions when used with mefloquine. Antacids or kaolin can reduce absorption, so separate dosing by at least 4 hours. Cimetidine can inhibit metabolism.
Answer: Adults: 150 to 300mg of Chloroquine base daily during periods of intense light exposure. Children: Up to 3mg/kg daily.
Answer: Excessive doses can cause retinal or visual field changes. Do not give to patients taking MAO inhibitors or within 2 weeks of discontinuing them. Patients allergic to Chloroquine should take an antihistamine beforehand.
Answer: No adverse effects have been reported in 100 pregnant patients. However, it's advisable to stop use unless absolutely necessary if adverse effects occur.
Answer: Adverse effects are usually due to overdosage or misuse and include: Psychotic episodes, convulsions, hypotension, cardiovascular collapse. ECG changes, double vision, difficulty focusing. Long-term effects: hair bleaching, skin pigmentation, photosensitivity, hearing loss, neuropathy, myopathy.
Answer: Empty the stomach through emesis or aspiration and lavage. Intravenous fluids and vasopressors may be needed for hypotension.
Answer: Pack of 60 ml.
Answer: Store below 30°C, keep away from light.