Ceflonac-Forte tabl. #10

Ceflonac-Forte tabl. #10

Fredun Pharmaceuticals
paracetamol 500.0 mg + aceclofenac 100.0 mg
2 bought
4.4
Available now!
840 00

What are the active ingredients in Ceflonac-Forte tablets?

Aceclofenac (100mg) and Paracetamol (500mg).

How does Aceclofenac work?

Aceclofenac inhibits the production of prostaglandins by blocking the enzyme cyclooxygenase.

What is the primary action of Paracetamol?

Paracetamol is an analgesic and antipyretic (fever reducer), with weak anti-inflammatory effects. It works by raising the pain threshold and inhibiting COX in the brain.

What conditions is Ceflonac-Forte indicated for?

Severe pain and inflammation in conditions like osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, low back pain, dental pain, gynecological pain, and painful/inflammatory conditions of the ear, nose, and throat.

What is the therapeutic category of Ceflonac-Forte?

It is categorized as a non-steroidal anti-inflammatory drug (NSAID), analgesic, and antipyretic agent.

How is Ceflonac-Forte administered?

Orally.

What is the recommended dosage?

1 tablet twice daily.

Are there any dosage adjustments needed for elderly patients or those with mild renal impairment?

Generally, no dose adjustments are necessary in these cases.

Is Ceflonac-Forte safe for children?

Safety and efficacy have not been established in children.

When is Ceflonac-Forte contraindicated?

In patients with: Sensitivity to aceclofenac, paracetamol, or any excipients of the product. History of aspirin or other NSAID-induced bronchospasm, rhinitis, or urticaria. Active or suspected peptic ulcer, gastrointestinal bleeding, or bleeding disorders. Severe heart failure, hypertension, hepatic or renal insufficiency. Third trimester of pregnancy.

What are the most common side effects of Ceflonac-Forte?

Gastrointestinal problems like dyspepsia, abdominal pain, nausea, and diarrhea.

Are there any rare side effects?

Yes, rarer side effects include dizziness, constipation, vomiting, ulcerative stomatitis, rash, dermatitis, headache, fatigue, allergic reactions, anemia, granulocytopenia, thrombocytopenia, neutropenia, edema, palpitations, leg cramps, flushing, purpura, paresthesia, tremors, gastrointestinal bleeding, gastrointestinal ulceration, pancreatitis, interstitial nephritis, depression, abnormal dreaming, somnolence, insomnia, vasculitis, hypoglycemia, and elevated blood urea, serum creatinine, and serum potassium levels.

What precautions should be taken when using Ceflonac-Forte?

It can cause dizziness, so avoid driving or operating machinery. Regular monitoring of renal function, liver function, and blood counts is required for patients on long-term treatment. Use with caution in patients with: Hepatic porphyria, coagulation disorders, history of peptic ulcers, ulcerative colitis, Crohn's disease, systemic lupus erythematosus (SLE), cerebrovascular bleeding, pregnancy, and lactation. Mild to moderate impairment of cardiac, hepatic, or renal function, and in elderly patients.

What are the known drug interactions with Ceflonac-Forte?

Aceclofenac: May increase plasma concentrations of lithium, digoxin, and methotrexate. May enhance the activity of anticoagulants. May inhibit the activity of diuretics. May increase cyclosporine nephrotoxicity. May precipitate convulsions when co-administered with quinolone antibiotics. Paracetamol: Increased risk of toxicity when co-administered with other hepatotoxic drugs or drugs that induce hepatic microsomal enzymes (e.g., rifampicin, isoniazid, chloramphenicol, anti-epileptic drugs, antiviral drugs). Absorption increased by metoclopramide, but excretion and plasma concentration altered by probenecid. Absorption reduced by cholestyramine.

Is co-administration with other NSAIDs or corticosteroids recommended?

No, co-administration with other NSAIDs or corticosteroids is to be avoided due to increased risk of side effects.

What are the symptoms of Ceflonac-Forte overdosage?

Nausea, vomiting, abdominal pain, dizziness, somnolence, headache, sweating, pancreatitis, hepatic failure, and acute renal failure.

What is the treatment for Ceflonac-Forte overdosage?

Gastric lavage, activated charcoal, and other symptomatic measures as per medical advice.

How should Ceflonac-Forte be stored?

Below 30°C, protected from light and moisture. Keep out of reach of children.

What is the presentation of Ceflonac-Forte?

1x10 tablets.


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