Clofenac-SR 100 mg tabl. #100

What is Clofenac-SR?

A non-steroidal anti-inflammatory drug (NSAID) containing diclofenac sodium, designed for slow-release pain relief and inflammation reduction.

What does Clofenac-SR look like?

Round, pink, film-coated tablets with beveled edges and shallow convex faces.

What is the active ingredient in Clofenac-SR?

Diclofenac sodium, 100 mg per tablet.

How does Clofenac-SR work?

Inhibits the enzyme cyclo-oxygenase, reducing prostaglandin and thromboxane production, thereby decreasing pain and swelling.

What is the recommended dosage for Clofenac-SR?

One 100 mg tablet orally once a day for adults.

When should Clofenac-SR be taken?

Swallowed whole, preferably with food.

What conditions is Clofenac-SR used to treat?

Rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, acute gout, post-surgical pain.

Who should not take Clofenac-SR?

Known hypersensitivity to diclofenac sodium, asthma/urticaria/rhinitis with aspirin/NSAID use, active/suspected peptic ulcer/gastrointestinal bleeding, bone marrow depression.

What are the common side effects of Clofenac-SR?

Nausea, headaches, diarrhea, epigastric pain, anorexia, dyspepsia, flatulence, abdominal cramps, vertigo, dizziness.

Are there any serious side effects associated with Clofenac-SR?

Yes, gastrointestinal toxicity (bleeding, ulceration, perforation) can occur at any time.

What other potential side effects should I be aware of?

Skin rashes, central nervous system effects, kidney problems, liver effects, blood disorders, hypersensitivity reactions, cardiovascular effects, severe cutaneous reactions, hair loss, bullous eruptions, erythema multiforme, photosensitivity.

Does Clofenac-SR interact with other medications?

Yes, including lithium, digoxin, methotrexate, other NSAIDs, cyclosporine, quinolone antibiotics, potassium-sparing diuretics, anticoagulants, antidiabetic agents.

What happens if I overdose on Clofenac-SR?

Gastrointestinal symptoms, central nervous system effects, renal effects, potentially serious effects like gastrointestinal hemorrhage, acute renal failure, convulsions, coma.

What should I do if I suspect an overdose?

Seek medical attention immediately. Gastric lavage and activated charcoal may be used.

Who should take Clofenac-SR with caution?

History of gastrointestinal ulceration, haematemesis, or melaena, ulcerative colitis, Crohn's disease, haematological abnormalities, bleeding diathesis, elderly patients, renal/hepatic impairment, hepatic porphyria, dizziness/central nervous system disturbances, restricted sodium intake, frail/low-body weight patients.

Is Clofenac-SR suitable for use in children?

No.

Is Clofenac-SR safe to use during pregnancy or lactation?

Not advisable.

How should I store Clofenac-SR?

Below 25°C (77°F), protected from moisture.