Acycor tabl. #10
Manufacturer: Globela Pharma, India
Composition: aceclofenac 100.0 mg
What is the generic name and strength of Acycor Tablets #10?
Aceclofenac Tablets BP, 100mg per film-coated tablet.
What are the therapeutic indications for Acycor Tablets #10?
Relief of pain and inflammation in adults with: Osteoarthritis, Rheumatoid arthritis, Ankylosing spondylitis.
What is the recommended dosage for Acycor Tablets #10 in adults?
200mg daily, taken as two separate 100mg doses (one in the morning and one in the evening).
Is Acycor Tablets #10 safe for use in children?
No, there are no clinical data on its use in children.
How should Acycor Tablets #10 be administered?
Orally, swallowed whole with sufficient liquid, with or after food.
What are the contraindications for Acycor Tablets #10?
Hypersensitivity to aceclofenac or excipients, Active or recurrent peptic ulcer/haemorrhage, Previous hypersensitivity reactions to ibuprofen, aspirin, or other NSAIDs, Active bleeding or bleeding diathesis, Severe hepatic failure and renal failure, Established congestive heart failure (NYHA II-IV), ischemic heart disease, peripheral arterial disease, and/or cerebrovascular disease, History of gastrointestinal bleeding or perforation related to previous NSAIDs therapy, Pregnancy (especially last trimester), women attempting to conceive, and lactation.
What are the warnings and precautions associated with Acycor Tablets #10?
Use with caution in patients with: Elderly, Respiratory disorders, Cardiovascular, renal, and hepatic impairment, Renal impairment, Hepatic impairment, Cardiovascular and cerebrovascular effects, Gastrointestinal bleeding, ulceration, and perforation, SLE and mixed connective tissue disease, Dermatological reactions, Impaired female fertility, Hypersensitivity reactions, Haematological effects, Long-term treatment.
What are some of the important drug interactions associated with Acycor Tablets #10?
Potential interactions with: Other analgesics, including cyclooxygenase-2 selective inhibitors, Anti-hypertensives, Diuretics, Cardiac glycosides like digoxin, Lithium, Methotrexate, Mifepristone, Corticosteroids, Anti-coagulants, Quinolone antibiotics, Anti-platelet agents and SSRIs, Ciclosporin, tacrolimus, Zidovudine, Antidiabetic agents, Other NSAIDs.
Is Acycor Tablets #10 safe to use during pregnancy and lactation?
Contraindicated during pregnancy and lactation.
What are the most common adverse effects associated with Acycor Tablets #10?
Gastrointestinal effects: Peptic ulcers, perforation, or GI bleeding, Nausea, vomiting, diarrhoea, flatulence, constipation, dyspepsia, abdominal pain, Melena, haematemesis, ulcerative stomatitis, Exacerbation of colitis and Crohn's disease, Gastritis, Hypersensitivity reactions, Cardiovascular and cerebrovascular effects.
What is the mechanism of action of aceclofenac?
Inhibits prostaglandin synthesis by inhibiting the enzyme cyclooxygenase.
What are the pharmacokinetic properties of aceclofenac?
Rapid and complete absorption, peak plasma concentrations in 1.25 to 3 hours, penetrates into synovial fluid, volume of distribution is approximately 25 L, mean plasma elimination half-life is around 4 hours, highly protein-bound, primarily excreted via urine.
What are the preclinical safety data for aceclofenac?
Consistent with those expected for NSAIDs, principal target organ being the gastrointestinal tract. No unexpected findings, not mutagenic or carcinogenic. Animal studies showed no evidence of teratogenesis in rats, but treatment in rabbits resulted in morphological changes in some fetuses.
Who manufactures and markets Acycor Tablets #10?
Manufactured by M/S. GLOBELA PHARMA PVT. LTD. in Surat, Gujarat, India and marketed by M/S. REALS PHARMACEUTICALS LIMITED in Lagos, Nigeria.
What is the price of Acycor tabl. #10?
The price of Acycor tabl. #10 is ₦ 750.00, exclusively for online orders through the Intaila mobile application