Anorol tabl. #100
Manufacturer: Hovid, Malaysia
Composition: orphenadrine 35.0 mg + paracetamol 450.0 mg
What is the composition of Anorol Tablet?
Anorol Tablet contains 450 mg of paracetamol and 35 mg of orphenadrine citrate.
What are the actions and pharmacology of Anorol Tablet's ingredients?
- Paracetamol: Analgesic (pain-relieving) and antipyretic (fever-reducing). Inhibits prostaglandin synthesis centrally and blocks pain-impulse generation peripherally.
- Orphenadrine Citrate: Depresses polysynaptic reflexes centrally, providing muscle relaxation.
How is Anorol Tablet absorbed and excreted?
Anorol Tablet is well absorbed orally, metabolized in the liver, and excreted in the urine.
What are the indications for using Anorol Tablet?
Relief of mild to moderate pain associated with acute musculoskeletal disorders and tension headaches.
What are the contraindications for using Anorol Tablet?
- Acute porphyria
- Aspirin-sensitive asthmatics
- Conditions where anticholinergic effects are undesirable
What are the warnings and precautions associated with Anorol Tablet?
- Caution in hepatic/renal impairment, glaucoma, cardiac arrhythmias, coronary insufficiency, or peptic ulceration.
- Avoid chronic use unless directed by a physician.
- Safety during pregnancy and lactation is not established.
- Usual antimuscarinic precautions should be observed with orphenadrine.
- Avoid concurrent use with other paracetamol-containing medicines.
What are the common side effects of Anorol Tablet?
- Dry mouth
- Mydriasis
- Cyclopegia
- Urinary urgency
- Constipation
- Mental confusion
What are the rare side effects of Anorol Tablet?
- Blood dyscrasias
- Hepatitis
- Hypersensitivity reactions
- Increased intraocular pressure
- Tachycardia
- CNS stimulation
- Transient lightheadedness, dizziness, or syncope
What drugs should not be used with Anorol Tablet?
- Hepatic enzyme-inducing agents
- General anesthetics
- CNS depressants
- MAO inhibitors
- Tricyclic antidepressants
What are the clinical features of Anorol Tablet overdose?
- Nausea, vomiting, or epigastric discomfort (first two days)
- Hepatic and renal failure (after 3-5 days)
- Metabolic acidosis
- Hypoglycemia
- Hypotension
- Sinus tachycardia
- Cardiac arrhythmias
- Coma
- Dry mouth
- Disturbance of visual accommodation and micturition
- Tachycardia
- Hyperthermia
- Dizziness
- Confusion
- Hallucinations
- Excitement
- Ataxia
- Convulsions
What is the treatment for Anorol Tablet overdose?
- Emesis or gastric lavage (if appropriate)
- Activated charcoal (may interfere with antidote)
- N-acetylcysteine (antidote) if plasma paracetamol level exceeds 150 ug/ml
- Symptomatic and supportive treatment
What is the recommended dosage and administration of Anorol Tablet?
- Adults: 1-2 tablets three to four times daily, up to a maximum of 8 tablets per day.
- Children: Not recommended.
How should Anorol Tablet be stored?
Store below 25°C, protected from light and moisture.
What are the presentation and packing details for Anorol Tablet?
Available in blisters of 10 x 10 tablets.
Who manufactures Anorol Tablet?
HOVID Bhd., Ipoh, Malaysia.
What is the price of Anorol tabl. #100?
The price of Anorol tabl. #100 is ₦ 7529.50, exclusively for online orders through the Intaila mobile application