Arotrix 5% cream tube 15.0 g #1
Manufacturer: Aristopharma, Bangladesh
Composition: permethrin 5.0 %
What is Arotrix Cream used for?
Arotrix Cream is a permethrin-based cream used to treat scabies and lice infestations.
How much Arotrix Cream should be used for different age groups?
Adults and children over 12 years: Up to 30g Children 6-12 years: Up to 15g Children 1-6 years: Up to 7.5g Children 2 months - 1 year: Up to 3.75g In some cases, adults may need up to 60g for full body application.
How should Arotrix Cream be applied?
Ensure skin is clean, dry, and cool. Apply the cream to the entire body (excluding the head), focusing on areas like fingers, toes, wrists, armpits, genitals, and buttocks. Wash the body thoroughly 8-12 hours after application. Reapply if any area of the body is washed with soap and water during treatment. A single application is typically sufficient. If necessary, reapply after seven days of the initial application.
What is the mechanism of action of Permethrin?
Permethrin disrupts the electrochemical processes across the membrane of excitable cells in insects, leading to sensory hyperexcitability, incoordination, and paralysis. It is believed to work similarly against mites.
How is Permethrin absorbed and metabolized?
Permethrin is absorbed through the skin. Less than 0.5% of the applied cream is absorbed in the first 48 hours. It is rapidly metabolized by ester hydrolysis into inactive metabolites that are primarily excreted in the urine.
Who should not use Arotrix Cream?
Individuals with a known allergy to permethrin, its inactive components, other pyrethroids, or pyrethrins should not use this cream.
Are there any precautions or warnings associated with using Arotrix Cream?
For external use only. Avoid contact with the eyes. If eye contact occurs, rinse with water or normal saline. Exercise caution when applying to the face of children, especially near the eyes and mouth. Nursing staff should wear gloves to prevent potential hand irritation. Discontinue use if hypersensitivity occurs. Persistent itching after treatment is not necessarily a sign of treatment failure, but living mites after 14 days require retreatment.
What are the potential side effects of Arotrix Cream?
Burning or stinging: Common, particularly in patients with severe scabies, usually mild and temporary. Erythema, edema, eczema, rash: These are considered part of the natural history of scabies. Itching: May persist due to allergic reactions to dead mites, but does not indicate treatment failure.
Is it safe to use Arotrix Cream during pregnancy or breastfeeding?
Limited data exists for use in pregnancy, but no risk to the fetus has been reported. Permethrin absorption is minimal (less than 0.5%), making the risk to the fetus minimal. It is unknown whether Permethrin is excreted in breast milk, but due to minimal absorption, it is unlikely to pose a risk to the infant.
Are there any drug interactions with Arotrix Cream?
No known drug interactions with Permethrin. Hold treatment with corticosteroids for eczematous conditions, as they may worsen scabies infestations by suppressing the immune response to the mites.
What should be done in case of an overdose?
No cases of Arotrix Cream overdose have been reported. Symptomatic treatment is indicated. If a child accidentally ingests the cream, gastric lavage should be performed within 2 hours.
How should Arotrix Cream be stored?
Close the tube immediately after use. Store below 30°C and protect from light. Do not freeze.
What is the packaging of Arotrix Cream?
Arotrix Cream is available in tubes containing 15g and 30g of cream.
What is the price of Arotrix 5% cream tube 15.0 g #1?
The price of Arotrix 5% cream tube 15.0 g #1 is ₦ 3408.75, exclusively for online orders through the Intaila mobile application