Bazreal Quinine sol. for inject. and infus. ampoules 2.0 ml #10
Manufacturer: Shandong Xier Kangtai Pharmaceutical Co, China
Composition: quinine 300.0 mg/ml
What is the primary action of Quinine in treating malaria?
Quinine primarily acts as a schizontocide, suppressing the asexual cycle of malaria parasites in red blood cells.
Does Quinine prevent the relapse of all malaria infections?
No, Quinine does not prevent relapses of Plasmodium vivax infections.
When is Quinine used parenterally (injection or infusion)?
Parenteral Quinine is used for cerebral, severe, or complicated malaria, and when oral medication is not possible.
What are the contraindications for using Quinine?
Quinine is contraindicated for hypersensitivity, haemolysis, tinnitus, or optic neuritis.
What precautions should be taken when administering Quinine to patients with heart conditions?
Quinine should be used cautiously in patients with atrial fibrillation or other heart conditions.
How should Quinine be administered intravenously?
Intravenous Quinine should be administered as a slow, constant rate infusion over four hours.
What is the loading dose of Quinine for severely ill adults?
The loading dose is 20 mg quinine dihydrochloride per kg of body weight, intravenously over four hours.
What is the maintenance dose of Quinine for adults?
The maintenance dose is 10 mg quinine dihydrochloride per kg of body weight, intravenously every eight to twelve hours.
How should Quinine be administered to children?
For children, the dose is 25 to 30 mg per kg daily, divided into three doses, switching to oral therapy as soon as possible.
What is Cinchonism and how is it treated?
Cinchonism is a collection of side effects from Quinine use, typically resolving when Quinine is discontinued.
How does Quinine affect pregnant women?
Quinine should be avoided in pregnancy if possible, but may be necessary in life-threatening malaria.
What is the recommended infusion rate for Quinine in pregnant patients?
The infusion rate should not exceed 10 mg/kg every eight hours.
What are some potential side effects of Quinine?
Potential side effects include: Cinchonism, hypersensitivity reactions, renal damage, and cardiovascular disturbances.
What are the symptoms of Quinine overdose?
Overdose symptoms include: enhanced gastrointestinal, central nervous system, and cardiovascular disturbances, severe visual disturbances, convulsions, coma, and respiratory depression.
What is the presentation of Bazreal Quinine Injection?
Bazreal Quinine Injection is available in 2 mL ampoules in packs of 6, 10, 50, or 100.
What are the storage instructions for Bazreal Quinine Injection?
Store Bazreal Quinine Injection below 30°C, protected from light, and out of reach of children.