C-Zocain Plus sol. for inj. bottle 50.0 ml #1
Manufacturer: Bharat Parenterals, India
Composition: adrenaline 0.0125 mg + lidocaine hydrochloride 20.0 mg

What is C-Zocain Plus?
C-Zocain Plus is a local anesthetic and antiarrhythmic injection containing Lidocaine Hydrochloride and Adrenaline. It is used for local or regional anesthesia in various medical procedures.
What are the active ingredients in C-Zocain Plus?
Each ml contains:
- Lidocaine Hydrochloride BP: 20 mg
- Adrenaline: 0.0125 mg (As Adrenaline Acid Tartrate BP 0.0225 mg)
What are the inactive ingredients in C-Zocain Plus?
- Sodium Metabisulphite BP (Buffering Agent): 0.50 mg
- Sodium Chloride BP (Buffering Agent): 6 mg
- Methyl Paraben BP (Preservative): 1 mg
- Water for Injection BP: q.s.
What are the indications for using C-Zocain Plus?
C-Zocain Plus is indicated for local or regional anesthesia by various techniques, including:
- Infiltration: Precutaneous injection
- Peripheral Nerve Block: Brachial plexus and intercostal blocks
- Central Neural Techniques: Lumbar and caudal epidural blocks
What are the recommended dosages for C-Zocain Plus?
The recommended dosage varies based on the type and extent of the procedure, patient factors, and required anesthesia depth.
- Odontological Anaesthesia: 1 to 1.5 ml for infiltration, 1.5 to 2 ml for nerve block, and 3 to 5 ml for oral surgery.
- General guideline: The maximum dose should not exceed 500 mg or 7 mg/kg of body weight.
What are the contraindications for using C-Zocain Plus?
C-Zocain Plus is contraindicated in patients with:
- Hypersensitivity: To local anesthetics of the amide type or any of the excipients.
- Metal Reactions: Local anesthetics react with certain metals, leading to the release of ions that can cause severe local irritation.
- Specific areas: C-Zocain Plus should not be used for anesthesia of fingers, toes, ear lobules, nose, and penis.
What are the potential adverse effects of using C-Zocain Plus?
C-Zocain Plus is generally safe but overdosage or accidental intravascular injection can cause toxic reactions. These reactions can include:
- Stimulation: Nervousness, dizziness
- Depression: Respiratory arrest, cardiovascular collapse, cardiac arrest
How can potential adverse effects be managed?
- Maintain Ventilation: Preferably using oxygen.
- Intravenous Infusion: Start an intravenous infusion with saline or glucose to maintain circulatory access for vasopressors and barbiturates.
- Circulatory Support: Use intravenous vasopressors to support circulatory collapse.
- Severe Convulsions: Administer small doses of a short-acting barbiturate or diazepam intravenously.
What are the precautions for using C-Zocain Plus?
- Minimize Dose: Always use the lowest possible concentration.
- Aspirate Before Injection: Aspirate before making an injection to avoid accidental intravascular injection, especially in vascular areas like the oral cavity.
- Premedication: Consider premedication with a short-acting barbiturate or diazepam as a prophylactic measure, especially with larger anesthetic doses.
How should C-Zocain Plus be stored?
- Cool Storage: Store in a cool place (below 30°C).
- Light Protection: Protect from light.
- Visual Inspection: Do not use if any particles are visible.
- Child Safety: Keep out of reach of children.
Where is C-Zocain Plus manufactured?
C-Zocain Plus is manufactured in India by Bharat Parenterals Ltd. and is manufactured for Chez Resources Pharma Nig Ltd., Nigeria.
Is C-Zocain Plus a prescription-only medicine?
Yes, C-Zocain Plus is a prescription-only medicine and can only be used by registered medical practitioners or hospitals.
What is the price of C-Zocain Plus sol. for inj. bottle 50.0 ml #1?
The price of C-Zocain Plus sol. for inj. bottle 50.0 ml #1 is ₦ 1038.12, exclusively for online orders through the Intaila mobile application