Cefuroxime 125 mg/5 ml powder for suspension bottle 70.0 ml #1
Manufacturer: Fidson healthcare , Nigeria
Composition: cefuroxime 25.0 mg/ml
What is the chemical name and molecular formula of Cefuroxime Axetil?
(RS)-1-hydroxyethyl (6R,7R)-7-[2-(2-furyl)glyoxyl-amido]-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]-oct-2-ene-2-carboxylate, 72-(Z)-(O-methyl-oxime), 1-acetate 3-carbamate. C₂₀H₂₂N₄O₁₀S
What is the indicated dosage of Cefuroxime 125mg Suspension for uncomplicated urinary tract infections in adolescents and adults?
125mg twice a day for 7 days.
How should FIDSON Cefuroxime 125mg Suspension be prepared for administration?
Reconstituted with previously boiled and cooled water according to label instructions.
How does food intake affect the absorption of Cefuroxime Axetil?
Absorption is enhanced when taken after food.
What is the mechanism of action of Cefuroxime Axetil?
It is hydrolyzed to cefuroxime, which inhibits bacterial cell-wall synthesis.
What are some common adverse reactions associated with Cefuroxime Axetil?
Gastrointestinal disturbances (diarrhea, nausea, vomiting, abdominal pain).
Is Cefuroxime Axetil contraindicated for any specific patient population?
Patients with a known allergy to cephalosporin antibiotics.
What precautions should be taken when prescribing Cefuroxime Axetil?
Caution in patients with concurrent potent diuretics, history of colitis or gastrointestinal malabsorption. Prolonged use may lead to superinfection.
How is Cefuroxime excreted from the body?
Unchanged in the urine.
How should Cefuroxime 125mg/5ml powder for oral suspension be stored?
Below 30°C, protected from light and moisture, and out of reach of children.
What is the role of Probenecid when administered with Cefuroxime Axetil?
Increases the serum concentration-time curve by 50%.
What are some of the infections Cefuroxime Axetil Suspension is indicated for?
Pharyngitis/Tonsillitis, Acute Bacterial Otitis Media, Acute Bacterial Maxillary Sinusitis, Acute Bacterial exacerbations of Chronic Bronchitis and Secondary Bacterial Infections of acute bronchitis, Uncomplicated Skin and Skin-Structure Infections, Uncomplicated Urinary Tract Infections, Uncomplicated Gonorrhea (urethral and endocervical), and Early Lyme Disease (erythema migrans).