Dermovate cream tube 30.0 g #1
Manufacturer: GlaxoSmithKline , Egypt
Composition: clobetasol 0.05 %
What is Dermovate cream used for?
Dermovate cream is a potent topical corticosteroid used to treat various skin conditions in adults, elderly individuals, and children over 1 year old. It effectively relieves inflammation and itching associated with psoriasis (excluding widespread plaque psoriasis), recalcitrant dermatoses, lichen planus, discoid lupus erythematosus, and other skin conditions not responsive to less potent steroids.
How is Dermovate cream applied?
Apply Dermovate cream thinly and gently rub into the affected area once or twice a day. Treatment duration is usually up to 4 weeks, after which the frequency or potency should be reduced. Allow time for absorption before applying an emollient.
What are the potential side effects of using Dermovate cream?
Common: Pruritus (itching), local skin burning/pain Uncommon: Skin atrophy, striae, telangiectasias Rare: Skin thinning, wrinkling, dryness, pigmentation changes, hypertrichosis, exacerbation of underlying symptoms, allergic contact dermatitis, pustular psoriasis, erythema, rash, urticaria, acne, application site irritation/pain
What are some precautions that should be taken when using Dermovate cream?
Use with caution in patients with a history of hypersensitivity to corticosteroids or excipients. Monitor for signs of hypercortisolism or HPA axis suppression, especially in children. Avoid long-term continuous use in infants and children under 12 years old. Be cautious in patients with psoriasis, as rebound relapses, tolerance development, and generalized pustular psoriasis are possible. Avoid application to the face, eyelids, or broken skin. Use appropriate antimicrobial therapy for infected lesions. Use with caution in pregnant and lactating women.
When is Dermovate cream contraindicated?
Untreated cutaneous infections Rosacea Dermatoses in children under one year of age Pruritus without inflammation Perianal and genital pruritus Perioral dermatitis
How is Dermovate cream stored?
Store Dermovate cream below 30°C. Refer to the packaging for shelf life information.
What is the active ingredient in Dermovate cream?
Clobetasol propionate 0.05% w/w
What are the inactive ingredients in Dermovate cream?
Cream: Cetostearyl alcohol, glyceryl monostearate, propylene glycol, citric acid (monohydrate), sodium citrate, chlorocresol, purified water, sorbitan sesquioleate. Ointment: White soft paraffin, beeswax substitute 6621, Arlacel 165, propylene glycol, purified water.
How does Dermovate cream work?
Dermovate cream is a potent topical corticosteroid that acts as an anti-inflammatory agent through various mechanisms. It inhibits late-phase allergic reactions by reducing mast cell density, decreasing chemotaxis and activation of eosinophils, inhibiting cytokine production, and blocking arachidonic acid metabolism.
Is Dermovate cream safe to use during pregnancy and lactation?
Dermovate cream is not recommended for use during pregnancy and lactation unless the potential benefits outweigh the risks to the fetus or infant. Limited data exists on its use in pregnant women, and topical corticosteroids can cause abnormalities in fetal development in animals. Further research is needed to determine its safety during breastfeeding.