Derm's Quinine sol. for inj. ampoules #10
Manufacturer: Shandong Xier Kangtai Pharmaceutical Co, China
Composition: quinine 300.0 mg/ml
Unordered Questions about Derm's Quinine Injection
What is the primary pharmacological action of quinine?
Quinine acts as a schizontocide, suppressing the asexual cycle of malaria parasites.
What are the indications for using Derm's Quinine Injection?
Treatment of acute malaria attacks, especially chloroquine-resistant or multi-drug-resistant strains.
When is quinine contraindicated?
Hypersensitivity to quinine, haemolysis, tinnitus, optic neuritis.
What precautions should be taken when using quinine?
Caution in patients with heart disease, myasthenia gravis, hypoprothrombinaemia, glucose-6-phosphate dehydrogenase deficiency.
What are the recommended dosage and administration routes for Derm's Quinine Injection?
Loading dose: 20 mg/kg IV infusion over 4 hours. Maintenance dose: 10 mg/kg IV infusion every 8-12 hours. IM injection is possible but may cause pain and necrosis.
What are the potential side-effects of quinine?
Cinchonism (ringing in ears, headache, nausea, vision problems), hypersensitivity reactions, renal damage, cardiovascular symptoms.
What are the symptoms of quinine overdose?
Enhanced side effects, visual disturbances, convulsions, coma, respiratory depression.
How should Derm's Quinine Injection be stored?
Below 30°C, protected from light, out of reach of children.
Is quinine safe for pregnant women?
Use with caution as it may cause hyperinsulinaemia, hypoglycaemia, abortion, and congenital malformations.
How does Derm's Quinine Injection compare to other malaria treatments?
Second-line treatment, used primarily for resistant strains or when oral medication is not possible. Newer drugs are often preferred.