Evolve HA eye drops bottle 10.0 ml #1
Manufacturer: C.O.C.Pharmaceuticals, Italy
Composition: hydrochloric (hcl) acid 0.2 %
What is Philo Promethazine Hydrochloride Injection?
Philo Promethazine Hydrochloride Injection is a sterile, pyrogen-free solution containing promethazine hydrochloride used for deep intramuscular or intravenous administration.
What are the indications for using Philo Promethazine Hydrochloride Injection?
- Ameliorating allergic reactions to blood or plasma
- As an adjunct to epinephrine and other standard measures in anaphylaxis
- For other uncomplicated allergic conditions
- For sedation and relief of apprehension
- Active treatment of motion sickness
- Prevention and control of nausea and vomiting
- As an adjunct to analgesics for postoperative pain control
- Preoperative, postoperative, and obstetric sedation
- Intravenously in special surgical situations
- With reduced amounts of meperidine or other narcotic analgesic
What are the contraindications for using Philo Promethazine Hydrochloride Injection?
- Pediatric patients less than 2 years of age
- Patients with known hypersensitivity to promethazine or other phenothiazines
- Subcutaneous injection
- Patients in a comatose state
- Intra-arterial injection
What are the important notes on administration of Philo Promethazine Hydrochloride Injection?
- Preferred route is deep intramuscular injection.
- Intravenous administration is tolerated but carries some hazard.
- Should not be administered subcutaneously.
- If administered intravenously, the concentration should not exceed 25 mg/ml at a rate of 25 mg per minute.
What is the recommended dosage for Philo Promethazine Hydrochloride Injection?
Dosage varies depending on indication and patient factors, but generally:
- Allergic conditions: 25 mg for adults, repeated within two hours if needed
- Sedation: 25 to 50 mg for adults
- Nausea and vomiting: 12.5 to 25 mg for adults, not to be repeated more frequently than every four hours
- Preoperative/postoperative medication: 25 to 50 mg for adults
- Obstetrics: 50 mg for early labor sedation, 25 to 75 mg for established labor
What are the potential side effects of Philo Promethazine Hydrochloride Injection?
- CNS: Drowsiness, sedation, blurred vision, dizziness, confusion, extrapyramidal symptoms, fatigue, etc.
- Cardiovascular: Increased/decreased blood pressure, tachycardia, bradycardia, etc.
- Dermatological: Dermatitis, photosensitivity, urticaria
- Hematologic: Leukopenia, thrombocytopenia, agranulocytosis
- Gastrointestinal: Dry mouth, nausea, vomiting, jaundice
- Respiratory: Asthma, nasal stuffiness, respiratory depression, apnea
What are the warnings associated with Philo Promethazine Hydrochloride Injection?
- Contains sodium metabisulfite which may cause allergic reactions.
- May impair mental and physical abilities.
- May lead to potentially fatal respiratory depression.
- May lower seizure threshold.
- Should be used with caution in patients with bone-marrow depression.
- Excessive doses in pediatric patients may cause sudden death.
- Dehydrated pediatric patients are more susceptible to dystonia.
What is the treatment for overdosage of Philo Promethazine Hydrochloride Injection?
Treatment is primarily symptomatic and supportive, focusing on:
- Monitoring vital signs
- Re-establishing adequate respiratory exchange
- Controlling convulsions with diazepam
- Correcting acidosis and electrolyte losses
What are the storage conditions for Philo Promethazine Hydrochloride Injection?
Store in a dark and dry place, below 30°C.
What is the shelf life of Philo Promethazine Hydrochloride Injection?
36 months.
What is the price of Evolve HA eye drops bottle 10.0 ml #1?
The price of Evolve HA eye drops bottle 10.0 ml #1 is ₦ 562.50, exclusively for online orders through the Intaila mobile application