Gloderm cream tube 30.0 g #1
Manufacturer: Evans Baroque , Nigeria
Composition: gentamycin 0.1 % + clotrimazole 1.0 % + beclomethasone 0.025 %
What are the active ingredients in Gloderm Cream and their respective concentrations?
Clobetasol Propionate BP: 0.05% w/w Miconazole Nitrate BP: 2.0% w/w Gentamicin Sulphate BP (equivalent to Gentamicin): 0.1% w/w
What is the pharmacological class of Gloderm Cream?
Topical corticosteroid with anti-fungal and antibacterial agents.
What is the mechanism of action of each active ingredient in Gloderm Cream?
Clobetasol Propionate: Anti-inflammatory, antipruritic, and vasoconstrictive properties by inducing phospholipase A inhibitory proteins. Miconazole Nitrate: Interferes with ergosterol biosynthesis in fungi. Gentamicin Sulphate: Interferes with bacterial protein synthesis by binding to ribosomal subunits.
How is each active ingredient in Gloderm Cream absorbed into the body?
Clobetasol Propionate: Absorbed through normal intact skin, increased absorption under occlusive dressings or in inflammation. Miconazole Nitrate: Minimal systemic absorption after topical application. Gentamicin Sulphate: Not usually absorbed from intact skin but readily absorbed from denuded areas.
What are the special precautions and warnings associated with Gloderm Cream?
Contact Dermatitis Systemic Effects Sensitization Pregnancy (Category C) Lactation
What are the indications for using Gloderm Cream?
Short-term relief of moderate-to-severe corticosteroid-responsive dermatoses with secondary bacterial and/or fungal infection.
What are the contraindications for using Gloderm Cream?
Hypersensitivity to clobetasol, miconazole, gentamicin, other amino glycosides, or any component of the preparation.
How should Gloderm Cream be applied?
Adults: Apply to affected area 2-3 times daily, or as directed by a physician. Elderly: Same as adults. Pediatrics: Not recommended for children under 12 years old.
What are the common adverse effects associated with Gloderm Cream?
Burning, stinging, irritation, itching, skin atrophy, dry skin, stinging, pruritus, cracking or fissuring of the skin, erythema, folliculitis, numbness of fingers, tenderness in the elbow, telangiectasia.
What are the potential drug interactions associated with Gloderm Cream?
Other corticosteroid-containing preparations. Vitamin K Antagonists (e.g., warfarin)
What should be done in case of an overdose of Gloderm Cream?
Overdose is not expected to be life-threatening, but long-term use of high doses can lead to adverse effects. Treatment is symptomatic and supportive.
What is the presentation of Gloderm Cream?
Aluminum collapsible tubes of 10 gm and 30 gm.
How should Gloderm Cream be stored?
Store below 30°C, protected from light.
Who manufactures and markets Gloderm Cream?
Manufacturer: Generics & Specialities Limited, India Marketer: Lincoln Pharmaceuticals Ltd., Nigeria
Where can I find more information about Gloderm Cream?
Lincoln Pharmaceuticals Ltd.: Email: info@lincolnpharma.com Website: www.lincolnpharma.com Generics & Specialities Limited: Email: info@gslnigeria.com
What is the price of Gloderm cream tube 30.0 g #1?
The price of Gloderm cream tube 30.0 g #1 is ₦ 1143.75, exclusively for online orders through the Intaila mobile application