P-Alaxin 40 mg/320 mg tabl. #9
Manufacturer: Bliss Pharma Limited , India
Composition: dihydroartemisinin 40.0 mg + piperaquine 320.0 mg
What is the composition of P-Alaxin tablets?
Each tablet contains 40 mg Dihydroartemisinin, 320 mg Piperaquine Phosphate, and excipients/coloring agents.
How should P-Alaxin be administered?
Orally, according to doctor's instructions, based on weight over three days.
What are the indications for using P-Alaxin?
Treatment of malaria caused by P. falciparum, P. vivax, and P. malariae.
What is the mechanism of action of Dihydroartemisinin?
Targets erythrocytic asexual malaria parasites, disrupts membranes, interferes with protein/nucleic acid synthesis.
What is the mechanism of action of Piperaquine Phosphate (PQP)?
Interferes with the food vacuole membrane of malaria trophozoites, leading to autophagocytosis.
What are the pharmacokinetic properties of Dihydroartemisinin?
Rapid absorption, peak concentration within 1 hour, half-life of 4 hours, excreted in urine and feces.
What are the pharmacokinetic properties of Piperaquine Phosphate?
Slower absorption, long half-life (20-22 days), eliminated through bile.
What are the potential adverse reactions associated with P-Alaxin?
Nausea, vomiting, reversible reduction in reticulocytes (DHA), dizziness, vertigo, headache, nausea, vomiting, abdominal discomfort, leucopenia, dyspnea, palpitations (PQP).
Are there any contraindications for P-Alaxin?
First trimester of pregnancy.
What precautions should be taken when using P-Alaxin?
Do not exceed stated dosage, caution during lactation.
How should P-Alaxin be stored?
In light-resistant containers below 30°C.
What is the packaging of P-Alaxin?
Blister packs of 9 tablets.
What is the price of P-Alaxin 40 mg/320 mg tabl. #9?
The price of P-Alaxin 40 mg/320 mg tabl. #9 is ₦ 1625.00, exclusively for online orders through the Intaila mobile application