P-Alaxin 5 mg/5 ml 40 mg/5 ml syrup bottle 80.0 ml #1

Manufacturer: Bliss Pharma Limited , India

Composition: piperaquine 8.0 mg/ml + dihydroartemisinin 1.0 mg/ml

Price: ₦ 2250.⁰⁰ Updated 16 Dec 2025

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How should P-Alaxin oral suspension be reconstituted?

Add boiled and cooled water to the 80ml mark, invert, and shake vigorously. Repeat if necessary. Shake well before every use. Refrigerate after reconstitution (stable for 7 days).

What is the mechanism of action of Dihydroartemisinin and Piperaquine Phosphate against malaria parasites?

• Dihydroartemisinin: Disrupts parasite membranes, inhibits protein and nucleic acid synthesis, and causes cytoplasmic vacuolization.
• Piperaquine Phosphate: Interferes with the food vacuole membrane, leading to autophagocytosis of trophozoites.

## What are the indications for using P-Alaxin? Treatment of malaria caused by P. falciparum, P. vivax, and P. malariae. ## What is the recommended dosage of P-Alaxin for a 10 kg child? 25 ml of the reconstituted suspension. ## What are the pharmacokinetic properties of Dihydroartemisinin and Piperaquine Phosphate?

• Dihydroartemisinin: Rapid absorption, peak concentration within 1 hour, half-life of ~4 hours, excreted in urine and feces.
• Piperaquine Phosphate: 80-90% absorbed within 24 hours, slow elimination, half-life of ~9.4 days, excreted through bile.

## What are the potential adverse effects of P-Alaxin? Nausea, vomiting, dizziness, vertigo, headache, abdominal discomfort, reversible leucopenia, dyspnea, and palpitations (infrequent). ## Are there any contraindications or precautions for using P-Alaxin? Not recommended during the first trimester of pregnancy. Lactation: excretion in breast milk unknown. Do not exceed stated dosage. ## How should P-Alaxin be stored? Unopened: Dry place below 25°C, protected from light. Reconstituted: Refrigerate (2°C to 8°C), stable for 7 days. Keep out of reach of children. ## What are the concentrations of Dihydroartemisinin and Piperaquine Phosphate in the reconstituted P-Alaxin suspension? Dihydroartemisinin: 1 mg/ml; Piperaquine Phosphate: 8 mg/ml. ## How is P-Alaxin supplied? Powder for oral suspension in an 80 ml bottle.

What is the price of P-Alaxin 5 mg/5 ml 40 mg/5 ml syrup bottle 80.0 ml #1?

The price of P-Alaxin 5 mg/5 ml 40 mg/5 ml syrup bottle 80.0 ml #1 is ₦ 2250.⁰⁰, exclusively for online orders through the Intaila mobile application