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Quinine sol. for inj. ampoules 2.0 ml #10 ​

Manufacturer: Laborate Pharmaceuticals, India

Composition: quinine 300.0 mg/ml

Price: Not availableQuinine sol. for inj. ampoules 2.0 ml #10

Unordered Questions and Detailed Answers for Quinine Injection 2.0 ml #10 ​

1. What is Quinine and what is it used for? ​

Quinine is a medication used primarily to treat malaria and babesiosis. It acts by suppressing the asexual cycle of development of malaria parasites in red blood cells (erythrocytes).

2. What is the strength of this Quinine injection? ​

300mg/ml.

3. What are the contraindications for using Quinine? ​

  • History of hypersensitivity to quinine
  • Haemolysis
  • Tinnitus or optic neuritis

4. What are some potential drug interactions with Quinine? ​

  • Antacids
  • Mefloquine
  • Rifamycins
  • Urinary alkanizers
  • Warfarin
  • Digoxin
  • Neuromuscular blocking agents
  • Antihistamines
  • Cinchona alkaloids
  • Hypoglycaemic drugs
  • Drugs affecting renal and hepatic impairment

5. What are the warnings associated with Quinine use? ​

  • Atrial fibrillation or other serious heart disease
  • Myasthenia gravis
  • Conditions where hypoprothrombinaemia could be a concern

6. What are the potential adverse effects of Quinine? ​

  • Hypersensitivity reactions
  • Haemolysis, haemoglobinaemia, haemoglobinuria
  • Gastrointestinal disturbances
  • Visual disturbances
  • Renal dysfunction
  • Cardiac disturbances

7. What are the precautions that need to be taken when using Quinine? ​

  • Stop administration immediately if haemolysis appears.
  • Dilute the concentrate to a strength not exceeding 30mg/ml before administration.

8. How is Quinine administered and what is the recommended dosage? ​

  • Intramuscular (IM) or slow intravenous (IV) injection only.
  • Dosage determined by the physician based on individual needs and condition.

9. How should Quinine be stored? ​

  • Below 25°C and protected from light.

10. Can Quinine be used during pregnancy and lactation? ​

  • Pregnancy: Avoid unless the benefits outweigh the risks.
  • Lactation: Contraindicated.

11. What are the symptoms of Quinine overdose and what is the antidote? ​

Symptoms: exacerbated adverse effects, including potential permanent visual disturbances and rare cases of sudden blindness.

  • Antidote: No specific antidote. Treatment is supportive and focuses on managing symptoms.