Rosulad-10 tabl. #30
Manufacturer: Globela Pharma, India
Composition: rosuvastatine 10.0 mg
What is the active ingredient in Rosulad-10?
Rosuvastatin Calcium USP, equivalent to 10mg of Rosuvastatin.
What is Rosulad-10 used to treat?
High cholesterol (hypercholesterolaemia) and prevent cardiovascular events.
How does Rosulad-10 work?
It lowers LDL-cholesterol, total cholesterol and triglycerides, while increasing HDL-cholesterol. It also lowers ApoB, nonHDL-C, VLDL-C, VLDL-TG and increases ApoA-I.
How is Rosulad-10 administered?
Orally, with or without food.
What is the recommended starting dose of Rosulad-10?
Individualised based on patient needs and response. Patients should be on a standard cholesterol-lowering diet.
How quickly does Rosulad-10 start to work?
Therapeutic effect within one week, with 90% of the maximum response achieved within two weeks.
What are the contraindications for Rosulad-10?
Hypersensitivity to Rosuvastatin or its excipients. Active liver disease. Severe renal impairment (creatinine clearance <30 ml/min). Myopathy. Concomitant Ciclosporin. Pregnancy, lactation, and women of childbearing potential not using contraception.
What are some of the potential side effects of Rosulad-10?
Renal effects, Skeletal muscle effects, Liver effects, Rash, Interstitial lung disease, Diabetes Mellitus.
What are the storage instructions for Rosulad-10?
Store below 30°C, protect from sunlight and moisture. Keep out of reach of children.
Who manufactures Rosulad-10?
Globela Pharma Pvt. Ltd. in India. The sole agent is Ladfield Global Resources Ltd in Nigeria.
What is the chemical name of Rosuvastatin?
(3R,5S,6E)-7-[4-(4-fluorophenyl)-2-(N-methylmethanesulfonamido)-6-(propan-2-yl)pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid
What is the molecular weight of Rosuvastatin?
481.539
What is the empirical/structural formula of Rosuvastatin?
C22H28FN3O6S
How is Rosuvastatin absorbed, distributed, metabolised, and excreted?
Absorption: Maximum plasma concentrations achieved about 5 hours after oral administration. Bioavailability about 20%. Distribution: Extensively taken up by the liver. Volume of distribution approximately 134 L. 90% binds to plasma proteins. Metabolism: Limited metabolism (about 10%). Main metabolites are N-desmethyl and lactone. Excretion: 90% excreted unchanged in faeces, 5% excreted unchanged in urine. Plasma elimination half-life about 19 hours.
What are some of the potential drug interactions with Rosuvastatin?
Transporter protein inhibitors, Ciclosporin, Protease inhibitors, Gemfibrozil and other lipid-lowering products, Ezetimibe, Antacids, Erythromycin, Cytochrome P450 enzymes.
What is the treatment for an overdose of Rosuvastatin?
No specific treatment. Symptomatic and supportive measures should be taken. Liver function and CK levels should be monitored. Haemodialysis unlikely to be beneficial.
What are the packaging details for Rosulad-10?
10 tablets packed in 1 AluAlu blister. 3 blisters packed in a printed duplex board carton with a package insert. Cartons packed in export-worthy shippers.
Does Rosulad-10 contain lactose?
Check the package insert or consult your doctor or pharmacist if you have lactose intolerance. The text does not explicitly state whether it contains lactose.
Is Rosulad-10 suitable for children?
The text mentions "Paediatric population" under warnings and precautions, suggesting it may not be suitable for children. Consult a doctor for specific advice.
Can I take Rosulad-10 while pregnant or breastfeeding?
Rosulad-10 is contraindicated during pregnancy and lactation. Women of childbearing potential should use appropriate contraceptive measures.
What is the price of Rosulad-10 tabl. #30?
The price of Rosulad-10 tabl. #30 is ₦ 2250.00, exclusively for online orders through the Intaila mobile application