Swidar 500/25 mg tabl. #3
Manufacturer: Swiss Pharma, Nigeria
Composition: sulfadoxine 500.0 mg + pyrimethamine 25.0 mg
What is Swidar and what is it used for?
Swidar is a combination medication containing sulfadoxine and pyrimethamine used for intermittent preventive treatment of malaria in pregnancy (IPT) during the second and third trimesters. It's also used with other antimalarials to treat falciparum malaria and has shown effectiveness against Toxoplasma gondii and Pneumocystis carinii pneumonia.
What is the composition of a Swidar tablet?
Each tablet contains 500mg of Sulfadoxine and 25mg of Pyrimethamine.
How is Swidar absorbed and eliminated from the body?
Peak plasma levels are reached after about 4 hours. Sulfadoxine has a half-life of ~200 hours and pyrimethamine ~100 hours. Elimination is primarily via the kidneys.
What are the potential side effects of Swidar?
Side effects can include hematological issues (e.g., anemia, thrombocytopenia), skin reactions (e.g., rash, Stevens-Johnson syndrome), gastrointestinal problems (e.g., nausea, vomiting), CNS effects (e.g., headache, convulsions), respiratory issues, genitourinary problems (e.g., renal failure), and miscellaneous effects (e.g., fever, chills).
Who should not take Swidar?
Those with hypersensitivity to ingredients, renal or hepatic failure, blood dyscrasias, megaloblastic anemia due to folate deficiency, infants under 2 months, pregnant women in the first trimester, and HIV-infected patients on cotrimoxazole prophylaxis.
What are the important warnings and precautions associated with Swidar?
Fatalities can occur from severe reactions. Discontinue at the first sign of rash, blood cell count drop, or infections. Use with caution in pregnancy/breastfeeding and in patients with impaired renal/hepatic function, folate deficiency, allergies, or asthma. Hemolysis may occur in individuals with G6PD deficiency. Avoid excessive sun.
What should I do in case of a Swidar overdose?
Seek immediate medical attention. Treatment may include activated charcoal, fluids, and anticonvulsants.
What are the drug interactions with Swidar?
Chloroquine may increase adverse reactions. Avoid antifolic drugs during malaria prophylaxis with Swidar. No reported interaction with antidiabetic agents.
How should Swidar be stored?
Below 30°C, protected from moisture and light, and out of reach of children.
What is the dosage and administration for Swidar in pregnant women for malaria prevention?
One full dose during the second and third trimesters, with the last dose no later than one month before delivery. Dosage depends on weight and should be determined by a physician.
What is the price of Swidar 500/25 mg tabl. #3?
The price of Swidar 500/25 mg tabl. #3 is ₦ 562.50, exclusively for online orders through the Intaila mobile application