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Vitamin B-Complex sol. for inj. bottle 10.0 ml #1 ​

Manufacturer: M.S Globla Overseas, India

Composition: vitamin B complex

Price: Not availableVitamin B-Complex sol. for inj. bottle 10.0 ml #1

What is the composition of Vitamin B-Complex Injection? ​

Each 10ml vial contains:

  • Vitamin B1 (BP) - 10mg
  • Vitamin B2 (BP) - 0.5mg
  • Vitamin B6 (BP) - 1mg
  • Nicotinamide (BP) - 10mg
  • Dex Panthenol (USP) - 1mg
  • Benzyl Alcohol (BP) - 2% viv
  • Water for Injections (BP) - qs

What is the mechanism of action of Vitamin B-Complex? ​

Vitamin B-Complex consists of several vitamins that each play a crucial role in various metabolic processes. They influence:

  • Carbohydrate, protein and lipid metabolism: Vitamins B1, B2, B6, and Nicotinamide participate in various enzyme systems that regulate these metabolic pathways.
  • Neural impulse conduction: Vitamin B1 plays a role in nerve function.
  • Tissue respiration: Nicotinamide contributes to oxygenation and restoration processes crucial for cell respiration.
  • Hemoglobin synthesis: Vitamin B2 is involved in the synthesis of hemoglobin.
  • Normal functioning of the nervous system, skin, and gastrointestinal tract: Vitamins B1, B6, and Nicotinamide contribute to the healthy functioning of these systems.

What are the indications for using Vitamin B-Complex Injection? ​

Vitamin B-Complex is indicated for various conditions related to vitamin B deficiency, including:

  • Neuritis (inflammation of nerves)
  • Alcohol, toxic, and post-infectious polyneuritis
  • Diabetic polyneuropathy
  • Neuralgia (nerve pain)
  • Sciatica
  • Central spastic conditions
  • Myasthenia (muscle weakness)
  • Paresthesia (numbness or tingling)
  • Atherosclerosis
  • Wernicke's encephalopathy
  • Vegetative neurosis
  • Dermatitis, neurodermatitis, psoriasis, lupus erythematosus, furunculosis
  • Stomatitis, cheilitis, glossitis, colitis, hepatitis
  • Chronic alcohol abuse
  • Asthenia (weakness)
  • Anemia
  • Intoxications

What are the contraindications for using Vitamin B-Complex Injection? ​

The main contraindication is hypersensitivity to the ingredients. It may cause mild allergic reactions, which are rare.

How is Vitamin B-Complex Injection administered and what is the usual dosage? ​

Route: Intramuscular or slow intravenous injection.

  • Usual adult dosage: 1-2 mL per injection intramuscularly daily or 2-3 times weekly, depending on the severity of the condition.

What are the precautions to be taken while administering Vitamin B-Complex Injection? ​

  • Observe the usual precautions for parenteral administration.
  • Do not inject if precipitation occurs.
  • Inject slowly by the intravenous route.
  • High concentrations should be diluted with Normal Saline Injection when given intravenously.

What are the possible adverse effects of Vitamin B-Complex Injection? ​

While well-tolerated, rare adverse effects in predisposed patients may include:

  • Itching
  • Urticaria (hives)
  • Quincke's edema (swelling under the skin)

What are the potential drug interactions with Vitamin B-Complex Injection? ​

Vitamin B-Complex may interact with various medications, including:

  • Adrenoreceptor blockers and adrenolytics: May reduce the antihypertensive effect.
  • Barbiturates and glutethimide: May decrease the hypnotic effect.
  • Chlorpromazine: May increase the urine excretion of vitamin B6.
  • Probenecid: May inhibit tubular excretion and reabsorption of vitamin B1, reducing its excretion in urine.
  • L-Dopa: May reduce the antiparkinsonian effect.
  • Oral contraceptive agents, isoniazid, penicillamine, cicloserin, and thiosemicarbazones: May reduce the blood concentration of vitamin B12.

Store in a cool and dry place, protected from light. Keep out of reach of children.

What is the presentation of Vitamin B-Complex Injection? ​

10 x 10 ml Glass vials in a box.