Xasten 1 mg tabl. #100
Manufacturer: Jiangsu Pengyao Pharmaceutical , China
Composition: dexamethasone 1.0 mg
What is Xasten and what is its active ingredient?
Xasten is a corticosteroid medication containing Dexamethasone.
How does Xasten work?
Xasten primarily acts as a glucocorticoid, suppressing inflammation and immune responses.
What are the main uses of Xasten?
Xasten is used to treat a wide range of conditions, including:
- Suppression of inflammatory and allergic disorders
- Shock
- Diagnosis of Cushing's disease
- Congenital adrenal hyperplasia
- Cerebral edema
- Nausea and vomiting associated with chemotherapy
- Rheumatic diseases
When should Xasten not be used?
Xasten is contraindicated in:
- Patients with active infections uncontrolled by appropriate antimicrobial therapy
- Patients receiving high-dose systemic corticosteroid therapy or within 3 months after such therapy (live vaccines should not be given)
What are some important drug interactions with Xasten?
- Increased metabolism and reduced effects: Barbiturates, carbamazepine, phenyltoin, primidone, and rifampicin.
- Increased plasma concentrations: Oral contraceptives and ritonavir.
- Increased potassium loss: Thiazides and furosemide.
- Increased risk of hypokalemia: Amphotericin and bronchodilators containing xanthines or beta2 agonists.
- Increased gastrointestinal bleeding and ulceration: Nonsteroidal anti-inflammatory drugs (NSAIDs).
- Altered response to anticoagulants and increased requirement of antidiabetic and antihypertensive drugs.
- **Decreased serum salicylate concentrations and reduced effect of anticholinesterases.
What precautions should be taken when using Xasten?
Xasten should be used with caution in patients with:
- Heart failure
- Recent myocardial infarction
- Hypertension
- Diabetes mellitus
- Epilepsy
- Glaucoma
- Hypothyroidism
- Hepatic failure
- Osteoporosis
- Peptic ulceration
- Psychoses or severe affective disorders
- Renal impairment
How should Xasten be withdrawn?
After short courses at moderate doses, Xasten may be withdrawn without tapering the dose. However, after high-dose or prolonged therapy, gradual withdrawal is recommended.
What are the possible side effects of Xasten?
Xasten can cause various side effects, including:
- Gastrointestinal: Dyspepsia, peptic ulceration, abdominal distension, acute pancreatitis, esophageal ulceration, and candidiasis.
- Musculoskeletal: Proximal myopathy, osteoporosis, vertebral and long bone fractures, vascular osteonecrosis, and tendon rupture.
- Endocrine: Adrenal suppression, menstrual irregularities and amenorrhea, Cushing's syndrome, hirsutism, weight gain, negative nitrogen and calcium balance, increased appetite, and increased susceptibility and severity of infection.
- Neuropsychiatric: Euphoria, psychological dependence, depression, insomnia, increased intracranial pressure with papilloedema in children (usually after withdrawal), psychosis, and aggravation of schizophrenia and epilepsy.
- Ophthalmic: Glaucoma, papilloedema, posterior subcapsular cataracts, corneal or scleral thinning, and exacerbation of ophthalmic viral or fungal disease.
- Other: Impaired healing, skin atrophy, hypersensitivity, fluid and electrolyte disturbance, leucocytosis, nausea, malaise, and hiccups.
What should I do if I overdose on Xasten?
Overdosage symptoms are related to its mineralocorticoid or glucocorticoid effects. Seek immediate medical attention and treat symptomatically.
What is the usual dosage of Xasten?
For suppression of inflammatory and allergic disorders, the usual adult dosage is 0.5mg to 10mg daily.
How should Xasten be stored?
Store Xasten away from light in a cool and dry place below 30°C. Keep it out of reach of children. The shelf validity is 3 years.
What is the manufacturer of Xasten?
Xasten is manufactured by HUAZHONG PHARMACEUTICAL CO., LTD, located in Xiangyang, Hubei, China.
What is the price of Xasten 1 mg tabl. #100?
The price of Xasten 1 mg tabl. #100 is ₦ 1180.66, exclusively for online orders through the Intaila mobile application